Ampule to store a liquid medium dose transferrable into a device to be used, preferably a syringe fo
专利摘要:
An ampoule 10 is designed with an ampoule neck 13 formed on the ampoule container 11, which ampoule neck 13 on the one hand bears a closure piece which can be removed by means of a predetermined breaking point, and on the other hand is designed as a plug-in and retention ring for the insertion of the head of an application device, for example the receiving cone 17 of a hypodermic syringe 16, in such a way that, in the connected state, the application device and the ampoule are joined firmly to form one unit. The ampoule 10 is preferably made in one piece from a thermoplastic, preferably polypropylene, and for this reason has sufficient elastic resilience at the ampoule neck 13 to be widened elastically upon insertion of the head or receiving cone 17 and to ensure the firm holding together of the application device and ampoule 10 when connected. However, in order to let air in during aspiration of the ampoule contents, the ampoule neck 13 can be designed on the inside with an axial ventilation groove. …<IMAGE>… 公开号:SU1727518A3 申请号:SU894614233 申请日:1989-05-30 公开日:1992-04-15 发明作者:Дойссен Вернер;Дойссен Хайно 申请人:Стелла Кг Вернер Дойссен (Фирма); IPC主号:
专利说明:
Put the last device into the open neck of the ampoule and hold the used device, for example, a syringe for injections, with one hand, and with the other hand to draw the contents of the ampoule. Elastically stretching the neck of the ampoule does not represent a significant increase in costs, in particular when the entire ampoule consists entirely of elastically stretchable material, such as polypropylene. When the neck of the ampoule is predominantly shaped, it has at its free end a locking element that, through an annular predetermined fracture point, is integrally connected to the edge of the neck of the neck of the ampoule, and its own edge of the neck of the ampoule is designed as a funnel-shaped entry for the head or cone used device. In this case, the own entrance edge of the neck of the ampoule to form a funnel-shaped entry can advantageously be performed with a rounded bend. In this form, the locking element can have a part that is basically disk-shaped and located inside the marginal zone of the inlet, with a predetermined fracture point annularly covering the locking element located around the funnel-shaped input with a recess relative to its own edge of the neck of the ampoule. With this embodiment, the head of the device used, for example, the receiving cone of the syringe for injection, can be particularly reliably and simply inserted after removing the closure element in the marginal zone of the neck of the ampoule. The remnants of a given fracture point that remain when the locking element is removed fall on the outer surface of the head, respectively, of the receiving cone, and as a result, they are pressed against the peripheral wall of the neck of the ampoule so that the separation of particles of synthetic material from these remnants of the specified fracture point becomes impossible damage to the transfer of the contents of the ampoule to the device used, since the particles adhering to the remnants of a given fracture point are displaced from the peripheral surface of the head, respectively tween the receiving cone, radially outward and the obstacle are created to penetrate into the interior of the ampoule. Due to the ventilation device in the ampoule, which is closed when the ampoule is transported and closed when the ampoule is used and must be opened when the ampoule is used simultaneously with the neck of the ampoule, when the liquid contents of the ampoule are sucked by the device used, for example, a syringe for injection, air flows into the ampoule. This prevents the formation of a vacuum inside the ampoule container, which would counteract the absorption of the liquid contents of the ampoule by the device used. In order to form a ventilating method, the neck of the ampoule may have on its inner side a vent groove which may extend mainly in the axial direction of the neck of the ampoule. However, it is preferable to provide for the formation of a ventilation device next to the neck of the vial of a separate vent hole. The latter, in a preferred embodiment of the invention, may 0 is formed by a ventilation tube passing parallel to the neck of the ampoule and having a locking element that is broken together with the locking element of the neck of the ampoule. In order to prevent air passage from the ventilation tube to the neck of the ampoule with increased reliability, and thus to the device used, the tube of the ampoule can be made elongated in comparison with the neck of the ampoule inside the ampoule. The separate vent opening provided with the neck of the ampoule may also be a thinner punch space of the wall of the ledge of the ampoule. It is also possible to perform the vent tube separately and at a distance from the neck of the ampoule in the ledge of the ampoule or other part of the wall of the ampoule. The proposed ampoule is advantageously provided for use in conjunction with conventional injection syringes made for multiple use for suction of the liquid used and with a receiving cone for inserting the injection needle. With this in mind the neck 5 of the proposed ampoule is preferably performed with a larger axial length than the receiving cone of conventional injection syringes. Due to this, the receiving cone of the syringe inserted into the neck of the ampoule A positive-fit injection is covered by the neck of the ampoule, with the result that all the amount of fluid contained in the ampoule can be sucked into the injection syringe. 5 In one preferred embodiment according to the invention, the capacity of the ampoule together with the neck of the ampoule is formed integrally from a thermoplastic synthetic material, mainly polypropylene, and on its own the end opposite the neck of the ampoule, the capacity of the ampoule after filling tightly closed. The ampoule in this embodiment can be carried out in a manner similar to the known dosing container. The most preferable option is when the ampoule capacity can have a greater wall thickness in its part adjacent to the neck of the ampoule than in its part opposite its ampoule. Due to this, the capacity of the ampoule in the part adjacent to the neck of the ampoule is made less flexible than in the part opposite the neck of the ampoule. This provides the advantage that when the ampoule is grasped by the part adjacent to the neck of the ampoule, undesirable squeezing is prevented and, thus, the vial contents of the ampoule are displaced, but the ampoule can be fixedly fixed nonetheless. On the other hand (at the end remote from the neck of the ampoule) the wall of the container is sufficiently thin and flexible, so that after filling the ampoule it can be pressed and welded. The container of the ampoule can be made with a cylindrical outer shape and an open end, opposite the neck of the ampoule, made in one piece with the neck of the ampoule and its locking element with a handle due to being cast under pressure. The cylindrical outer shape provides the advantage that any further processing, in particular overprinting, and the supply within the filling and welding machine are substantially facilitated. In addition, the cylindrical outer shape provides the advantage that the inevitable increase in diameter at the welding site is noticeably smaller compared to the ampoules, which come from the conical shape of the ampoule capacity. The manufacture of ampoules according to the invention with a cylindrical outer shape of the ampoule ampoule can be difficult at first, but for this purpose the ampoule capacity can be made with an inner volume slightly tapered from the open end to the neck of the ampoule and, accordingly, with a wall thickness conically increasing from open end and to the neck of the ampoule. This significantly facilitates the extraction of the ampoule in the manufacture using injection molding, and also achieves the required performance of the vessel wall with less flexibility in the part adjacent to the neck of the ampoule and more flexibility in the part remote from the neck of the ampoule. When making as a whole an ampoule of synthetic material, the transition from the ampoule capacity to the ampoule neck can be further performed as a ledge of the ampoule, on which the blind embossing is made, for example for indicating the volume and containing the corresponding ampoule. This blind embossing on the ledge of the ampoule inevitably falls when the ampoule is grabbed for opening and when the ampoule is attached to the device used in the user's field of view, so that the vial can be additionally ensured that the ampoule is open before opening and articulating with the device used. and the correct amount. In addition, an emptied ampoule can be stored as a control. All further specifications, such as batch number, date of manufacture, date 0 expiration dates can be squeezed out on the day the ampoules are filled in the form of blind embossing with the press pads of a welding machine in the resulting weld. 5 In FIG. 1 shows a filled, fitable, ampoule according to the invention, side view; in fig. 2 shows an embodiment of the ampoule according to the invention before filling, axial section; in fig. 0 3 - the same, the second form of implementation; in fig. 4 - zone 4 in FIG. 3, increased scale; in fig. 5 - zone 5 in FIG. 1, side view, enlarged scale; in fig. 6 - free end zone of the neck of the ampoule according to 5 of the invention, axial partial section; in fig. 7 shows section A-A in FIG. 3; in fig. 8 - neck of the ampoule with a locking element, axial section, top view; in fig. 9 - ampoule with injection syringe installed for drawing the ampoule, general view; in fig. 10 - zone 1 in FIG. 9, enlarged partial section; in fig. 11 is an ampoule with a preferred form of carrying out the invention, the remainder of 5, the wall of the ampoule basically corresponds to the embodiment according to FIG. 3, axial partial section; in fig. 12 is a section BB in FIG. eleven; in fig. 13 - ampoule according to FIG. 11 and 12 in the direction of the arrow 0 V in FIG. 11, side view; in fig. 14 - ampoule according to FIG. 11-13 in the direction of arrow C in FIG. 13, top view; in fig. 15 shows an embodiment of an ampoule according to FIG. 11, depicted in the same manner as in FIG. 5 11, partial section. Ampoule 1 for receiving a dose of a liquid medium transferred to the device used 2, preferably an injection syringe, comprising a housing 3 with a neck 4 with an entry zone 5 for introducing a conical head 6 of the device used 2 and with the locking element 7, which through the annular predetermined fracture point 8 is integrally connected to the marginal zone 9 of the contents of the ampoule 1 entering the used device 2. The neck 4 of the ampoule 1 is elastic, in cross section it has the shape of a ring and provided with a vent 10 leading into the vial. Own edge 11 of the entrance of the ampoule 1 is designed as a funnel-shaped entrance for the head 12 of the device used 2 (syringe for injection). Own edge 13 of the entrance of the neck 4 is made with a rounding. The locking element 7 is made with a disc-shaped element 14 and is located inside the zone 5 of the entrance, moreover, the predetermined fracture point 8 is located around the funnel-shaped entrance with a recess relative to its own marginal zone 13 of the entrance of the neck 4 ampoule 1. The valve 10 is made in the form of a groove 15 located on the inside of the neck 4 of the ampoule and of the ampoule 1 extending parallel to the longitudinal axis of the neck 4, or as a separate vent hole, which is a tubular channel 16, extending parallel to the neck 4 of the ampoule 1. Ex the tubular duct 16 provided with a locking member formed integrally with the closing element 7 of the neck 4 of the ampoule 1. The tubular channel 16 is longer than the ampoule neck 4, and the projecting end 17 a channel 16 is inside the ampoule 1. Ampoule 1 is made of thermoplastic synthetic material, preferably propylene, and the end of body 3, opposite to neck 4 of ampoule 1, after filling, is hermetically sealed with cross seam 18. The housing 3 of the ampoule 1 is provided with a wall 19 having a different thickness of 20 and 21 continuously increasing inside the housing 3 of the ampoule 1 from the closed end to the neck 4 of the ampoule 1. At the junction of the housing 1 to the neck 4 of the ampoule 1, a step 22 is formed on which blind embossings 23 are made for marking. The ampoule is used as follows. The locking element 7 is removed by loosening at the same time breaking and breaking. The head of the receiving device is inserted into the neck 4 of the ampoule 1, which, due to the elasticity of the material, is tightly fixed in the neck 4 of the ampoule. When the contents are dragged from the ampoule, air enters the cavity of the body 3 of the ampoule 1 through the vent device 10. On the ampoule 1 blint embossing 23 is made, giving information about the content and volume of the ampoule. The proposed ampoule design makes it easier to transfer the contents of the ampoule to an instrument used, such as a syringe, and improves reliability when using it.
权利要求:
Claims (12) [1] 1. An ampoule for placing a dose of a liquid medium transferred to the device used, preferably an injection syringe, comprising a body having a neck with an entrance area for entering the conical head of the device used and with a locking element that is integrally connected through an annular predetermined break point with the marginal zone of entry of the contents of the ampoule into the instrument used, characterized in that, in order to facilitate the transfer of the contents of the ampoule into the instrument used and to increase reliability, the neck of the ampoule is made elastic, in cross section The air is shaped like a ring and is provided with a ventilation device leading inside the ampoule. [2] 2. Ampoule according to Claim 1, characterized in that the own entrance edge of the ampoule is designed as a funnel-shaped input for the head of the instrument used. [3] 3. Ampoule according to claim 1 or 2, characterized in that the own entrance edge of the neck of the ampoule is made with rounding. [4] 4. Ampoule in one of the paragraphs. 1-3, characterized in that the locking element is made with a disc-shaped element and is located inside the entrance zone, the predetermined break point located around the funnel-shaped entrance with a recess relative to its own marginal zone of the neck of the ampoule. [5] 5. Ampoule in one of the paragraphs. 1-4, characterized in that the ventilation device is made in the form of a groove located on the inner side of the neck of the ampoule and extending parallel to the longitudinal axis of the neck of the ampoule. [6] 6. Ampoule in one of the paragraphs. 1-4, in which there is a separate vent hole adjacent to the neck of the ampoule. [7] 7. Ampoule according to claim 6, wherein the ventilation device is a tubular channel extending parallel to the neck of the ampoule, wherein the tubular channel is provided with a locking element made integral with the locking element of the neck of the ampoule. [8] 8. Ampoule according to claim 7, characterized in that the tubular channel is longer the neck of the ampoule and the protruding end of the channel are located inside the ampoule. [9] 9. Ampoule in one of the paragraphs. 1-8, except for the fact that the ampoule is made of thermoplastic synthetic material, preferably propylene, and the end of the body opposite the neck of the ampoule is sealed after filling. [10] 10. Ampoule according to claim 9, characterized in that the closed end of the body of the ampoule is welded by a transverse seam. 0 [11] 11. Ampula. According to one of paragraphs. 8-10, characterized in that the body of the ampoule made with a wall having a different thickness, continuously increasing inside the body of the ampoule from the closed end to the neck of the ampoule. [12] 12. Ampoule in one of the paragraphs. 9-11, characterized in that at the place of transition of the body into the neck of the ampoule, a step is formed, on which blind embossing for marking is made. FIG. 2 14 4 / 0H i X I X .four FIG. ten at P . Fie.11 6-6 FIG. 12 Fig.P FIG. / J FIG. 15
类似技术:
公开号 | 公开日 | 专利标题 SU1727518A3|1992-04-15|Ampule to store a liquid medium dose transferrable into a device to be used, preferably a syringe for making injections US4548601A|1985-10-22|Prepackaged, injectable pharmaceutical and hypodermic needle combination US4325369A|1982-04-20|Disposable container for a syringe US4505709A|1985-03-19|Liquid transfer device US5135514A|1992-08-04|Plastic cartridge and syringe JP2731756B2|1998-03-25|Needle dispenser for medication pens US4571242A|1986-02-18|Tamper proof cap for syringes and the like US4316462A|1982-02-23|Filtering device for an injection device US4132225A|1979-01-02|Micro blood collector US4950242A|1990-08-21|Hypodermic needle cover and assembly therewith US3578037A|1971-05-11|Method for filling a syringe US4007639A|1977-02-15|Capillary vessel for blood removal US4250893A|1981-02-17|Sample collection device US3552387A|1971-01-05|Combination syringe and vial JPH09215754A|1997-08-19|Tool used for liquid for medical use and connector used for the same EP1323446A2|2003-07-02|Syringe-type container for liquid medicine HU208249B|1993-09-28|Medicine-feeder first for treating the mammitis of animals US2693189A|1954-11-02|Venoclysis equipment AU665457B2|1996-01-04|Needle stopper and needle removal device US2667164A|1954-01-26|Syringe US2615446A|1952-10-28|Hypodermic syringe US5053020A|1991-10-01|Applicator having two cannulas EP3498126A1|2019-06-19|Ampoule for storing cosmetic liquid US1668588A|1928-05-08|Hypodermic syringe US2801741A|1957-08-06|Sterile container and ligature package
同族专利:
公开号 | 公开日 EP0344476A3|1990-03-28| JPH0245056A|1990-02-15| AU3597689A|1989-12-07| BR8902517A|1990-01-23| EP0344476A2|1989-12-06| DE3818682A1|1989-12-21| US4926915A|1990-05-22| EP0344476B1|1992-09-02| DE58902185D1|1992-10-08| JPH0588619B2|1993-12-22| ES2034471T3|1993-04-01|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 US1254655A|1917-06-14|1918-01-29|Paul Carpenter|Ampul.| US1487824A|1922-11-11|1924-03-25|Charles W Vincent|Funnel| US1641328A|1925-06-06|1927-09-06|Ferdinand Jules Alfred|Dosing flask| US1651963A|1926-05-18|1927-12-06|Mooney Jerome Henry|Funnel| US2668533A|1952-02-12|1954-02-09|Sterilon Corp|Medical apparatus| FR1066799A|1952-11-25|1954-06-09|Tube for pasty or other materials, process for manufacturing this tube and mold for carrying out the process or similar process| US2798488A|1954-09-15|1957-07-09|Merck & Co Inc|Syringe unit| US2878808A|1957-03-26|1959-03-24|Baxter Laboratories Inc|Parenteral solution container closure| NL272321A|1960-12-09| DE1966623B2|1969-01-02|1976-08-26|Ausscheidung aus: 19 65 761 Arias, Marcelo Chiquiar, Dr., Mexiko|Disposable container for sterile liquids for - contact lenses etc| US3667657A|1969-01-02|1972-06-06|Marcelo Chiqular Arias|Disposable container| US3777949A|1969-09-29|1973-12-11|Arias M Chiquiari|Improved single dose disposable container and accessories| NL7111800A|1970-08-27|1972-02-29| DE2653993C3|1976-11-27|1980-05-14|Stella-Kg Werner Deussen, 6229 Walluf|Container with breakable closure| SE412697B|1978-09-13|1980-03-17|Gambro Dialysatoren|CONNECTOR NECK FOR BLOOD FITTINGS OR SIMILAR| US4338980A|1980-01-14|1982-07-13|Schwebel Paul R|Device for filling medicament injectors| DE3382534D1|1982-02-08|1992-04-30|Astra Laekemedel Ab|CONTAINER FILLED WITH NORMAL DOSIS.| AT386123B|1986-05-26|1988-07-11|Pharmazeutische Fabrik Montavit Gmbh|PLASTIC CONTAINER FOR THE STORAGE AND APPLICATION OF A CATHETER LUBRICANT| GB8801655D0|1988-01-26|1988-02-24|Waverley Pharma Ltd|Ampoules| GB8802349D0|1988-02-03|1988-03-02|Waverley Pharma Ltd|Ampoule with luer| GB0800455D0|2008-01-11|2008-02-20|Prosidion Ltd|Compounds|DE3916840C2|1988-09-21|1993-06-09|Bernd 7166 Sulzbach-Laufen De Hansen| US5409125A|1989-12-11|1995-04-25|Aktiebolaget Astra|Unit dose container| AU622740B2|1989-12-11|1992-04-16|Astra Aktiebolag|Unit dose container| DK0532641T3|1990-06-08|1996-09-02|Astra Ab|Pre-filled disposable device for introducing a pharmacologically active substance into a patient's body cavity, a method of manufacturing the device, and casting apparatus for making the device| US5224937A|1991-06-21|1993-07-06|Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V.|Closed syringe-filling system| FR2682088B1|1991-10-04|1994-06-10|Emballages Conditionnement|PACKAGING FOR THE EXTEMPORANEOUS PREPARATION OF MEDICINAL PRODUCTS.| US5807359A|1993-06-08|1998-09-15|Bemis Manufacturing Company|Medical suction system| US6358232B1|1994-12-29|2002-03-19|Bemis Manufacturing Company|Method and apparatus for removing and disposing of body fluids| US6244311B1|1994-12-29|2001-06-12|Bemis Manufacturing Company|Method and apparatus for removing and disposing of body fluids| US5688255A|1994-12-29|1997-11-18|Bemis Manufacturing Company|Method and apparatus for removing and disposing of body fluids| US5620428A|1994-12-29|1997-04-15|Bemis Manufacturing Company|Suction canister apparatus and method| US5683371A|1994-12-29|1997-11-04|Bemis Manufacturing Company|Suction canister apparatus and method| US5758637A|1995-08-31|1998-06-02|Aerogen, Inc.|Liquid dispensing apparatus and methods| DE29602173U1|1996-02-08|1997-06-26|Braun Melsungen Ag|Application device for medical liquids| SE9702636D0|1997-07-08|1997-07-08|Pharmacia & Upjohn Ab|Improvements related to medical containers| US6082575A|1998-03-09|2000-07-04|Pepsico, Inc.|Hybrid beverage container| US6235177B1|1999-09-09|2001-05-22|Aerogen, Inc.|Method for the construction of an aperture plate for dispensing liquid droplets| US7585292B2|2000-03-28|2009-09-08|Bemis Manufacturing Company|Medical suction apparatus and draining of same| WO2001072350A1|2000-03-28|2001-10-04|Bemis Manufacturing Company|Medical suction apparatus and methods for draining same| US7674248B2|2000-03-28|2010-03-09|Bemis Manufacturing Company|Medical suction apparatus and methods for draining same| US7971588B2|2000-05-05|2011-07-05|Novartis Ag|Methods and systems for operating an aerosol generator| US8336545B2|2000-05-05|2012-12-25|Novartis Pharma Ag|Methods and systems for operating an aerosol generator| US6434913B1|2000-09-15|2002-08-20|Thomas Hatch|Single-use syringe| US6672477B2|2001-01-12|2004-01-06|Bemis Manufacturing Company|Method and apparatus for disposing of bodily fluids from a container| US7100600B2|2001-03-20|2006-09-05|Aerogen, Inc.|Fluid filled ampoules and methods for their use in aerosolizers| US6948491B2|2001-03-20|2005-09-27|Aerogen, Inc.|Convertible fluid feed system with comformable reservoir and methods| EP1474196B1|2002-01-15|2016-08-17|Novartis AG|Methods and systems for operating an aerosol generator| WO2003057291A1|2002-01-07|2003-07-17|Aerogen, Inc.|Devices and methods for nebulizing fluids for inhalation| US7677467B2|2002-01-07|2010-03-16|Novartis Pharma Ag|Methods and devices for aerosolizing medicament| DE10209990B4|2002-03-07|2007-02-08|Rudolf Gantenbrink|Bottle and process for its production| AU2003256253A1|2002-05-20|2003-12-02|Aerogen, Inc.|Aerosol for medical treatment and methods| DE10226591B4|2002-06-14|2004-10-28|Rudolf Gantenbrink|Process for closing a hollow body made of glass, hollow body made of glass and kit| USD493526S1|2003-04-22|2004-07-27|Becton, Dickinson And Company|Syringe tip cap| US8616195B2|2003-07-18|2013-12-31|Novartis Ag|Nebuliser for the production of aerosolized medication| US20050101922A1|2003-11-07|2005-05-12|Bemis Manufacturing Company|Suction canister and drainage of same| US7946291B2|2004-04-20|2011-05-24|Novartis Ag|Ventilation systems and methods employing aerosol generators| EP1726285A1|2005-05-24|2006-11-29|ViforAg|Container for dispensing a medicament and associated administering apparatus| JP5064383B2|2005-05-25|2012-10-31|エアロジェン,インコーポレイテッド|Vibration system and method| US20070260691A1|2006-05-02|2007-11-08|Kallqvist Claes M|Wireless local area network capacity triggered upload and download| ZA200900042B|2006-07-04|2010-03-31|Yoshio Oyama|End portion for hermetically sealed container having fine opening surface obtained easily by cleavage| FR2908110B1|2006-11-03|2011-05-20|Seriplast|BULB COMPRISING A HOLLOW BODY AND A HEAD WITH POSSIBILITY OF RUPTURE BETWEEN THE BODY AND THE HEAD.| JP5452882B2|2008-04-30|2014-03-26|株式会社吉野工業所|Resin ampoule| US8337108B2|2008-06-26|2012-12-25|Elc Management Llc|Single-use cosmetic sampler| EP2872101B1|2012-07-13|2016-09-07|Becton, Dickinson and Company Ltd.|Medical vial access device with pressure equalization and closed drug transfer system and method utilizing same| JP6452026B2|2014-07-08|2019-01-16|大日本印刷株式会社|Injection container, container with injection, method of using container with injection, and method of storing injection in injection container| US10179678B2|2017-04-26|2019-01-15|The Hartz Mountain Corporation|Applicator with breakaway cap| DE102017007443A1|2017-08-05|2019-02-07|Kocher-Plastik Maschinenbau Gmbh|Blow molding, filling and closing method and then produced container product, in particular ampoule product| KR101955208B1|2017-12-18|2019-03-07|엘앤피코스메틱 |Ampoule for storing cosmetic liquid|
法律状态:
优先权:
[返回顶部]
申请号 | 申请日 | 专利标题 DE19883818682|DE3818682A1|1988-06-01|1988-06-01|AMPOULE| 相关专利
Sulfonates, polymers, resist compositions and patterning process
Washing machine
Washing machine
Device for fixture finishing and tension adjusting of membrane
Structure for Equipping Band in a Plane Cathode Ray Tube
Process for preparation of 7 alpha-carboxyl 9, 11-epoxy steroids and intermediates useful therein an
国家/地区
|